狄文

学术任职

上海交通大学医学院附属仁济医院妇产科主任，上海交通大学医学院女子计划生育第一研究室副主任，上海医学会妇产科学会主任委员，中华医学会妇产科学会委员，中华医学会妇科肿瘤学会委员，上海市产科质量控制专家委员会委员

科研成果

《中华妇产科杂志》编委，《现代妇产科进展》、《实用妇产科杂志》、《中国实用妇科与产科杂志》、《中华妇幼临床医学杂志》、《国外医学-计划生育分册》、《国外医学-妇幼保健分册》编委，全国七年制、八年制医学教材《妇产科学》编者。

文献发表

Ning Zhang, Hanwen Zhang, Li Xia, Ying Zheng, Yun Yu, Yuanshan Zhu, Guoqiang Chen, Wen Di. NSC606985 induces apoptosis, exerts synergistic effects with cisplatin, and inhibits hypoxia-stabilized HIF-1a protein in human ovarian cancer cells. Cancer Letters. 2009, 278:139-144.

Lan Dai, Liying Gu, Chuanwei Ding, Lihua Qiu, Wen Di. TWEAK promotes ovarian cancer cell metastasis via NF-kB pathway activation and VEGF expression. Cancer Letters. 2009, 283(2):159-167.

Cong Cao, Shan Lu, Alex Sowa, Rebecca Kivlin, Ashley Amaral, Wenming Chu, Hui Yang, Wen Di, Yinsheng Wan. Priming with EGFR tyrosine kinase inhibitor and EGF sensitizes ovarian cancer cells to respond to chemotherapeutical drugs. Cancer Letters. 2008, 266(2) :249-262.

Chao Ji, Cong Cao, Shan Lu, Rebecca Kivlin, Ashley Amaral, Nicola Kouttab, Hui Yang, Wenming Chu, Zhigang Bi, Wen Di, Yinsheng Wan. Curcumin attenuates EGF-induced AQP3 up-regulation and cell migration in human ovarian cancer cells. Cancer Chemother Pharmacol. 2008, 62:857-865.

Wei Pan, Hui Yang ,Cong Cao, Xiuzu Song,Brittany Wallin, Rebecca Kivlin, Shan Lu, Gang Hu, Wen Di, Yinsheng Wan. AMPK mediates curcumin-induced cell death in CaOV3 ovarian cancer cells. Oncology Reports. 2008, 20(6):1553-1559.

Shi J, Wan Y, Di W. Effect of hypoxia and re-oxygenation on cell invasion and adhesion in human ovarian carcinoma cells. Oncology Reports. 2008, 20(4):803-807.

Wen Di, Sun Wei Guo. The search for genetic variants predisposing women to endometriosis. Curr Opin Obstet Gynecol. 2007, 19(4):395–401.

Changlin Zhou, Lihua Qiu, Yun Sun, Sarah Healey, Harold Wanebo, Nicola Kouttab, Wen Di, Bingfang Yan, Yinsheng Wan. Inhibition of EGFR/PI13/AKT cell survival pathway promotes TSA’s effect on cell death and migration in human ovarian cancer cells. International Journal of Oncology. 2006, 29(1):269-278.

Qiu L, Zhou C, Sun Y, Di W, Scheffler E, Healey S, Kouttab N, Chu W, Wan Y. Crosstalk between EGFR and TrkB enhances ovarian cancer cell migration and proliferation. Int J Oncol. 2006, 29(4):1003-1011.

Qiu L, Zhou C, Sun Y, Di W, Scheffler E, Healey S, Wanebo H, Kouttab N, Chu W, Wan Y. Paclitaxel and ceramide synergistically induce cell death with transient activation of EGFR and ERK pathway in pancreatic cancer cells. Oncology Reports. 2006, 16(4):907-913.

S Zhang, Q D Lin, W Di. Suppression of human ovarian carcinoma metastasis by the metastasis-suppressor gene,BRMS1. Int J gynecol Cancer. 2006, 16(2):522-531.

Wu Zhenming, Di Wen. Clinical Diagnosis And Treatment Of Small Ovarian Tumor In Postmenopausal Women. Chinese Journal of Cancer Research. 2006, 18(3):229-234.

Li hua Qiu, Qun Wang, Wen Di, Qin Jiang, Erica Schefeller, Steve Derby, Harold Wanebo, Bingfang Yan, Yinsheng Wan. Transient activation of EGFR/AKT cell survival pathway and expression of surviving contribute to reduced sensitivity of human melanoma cells to betulinic acid. International Journal of Oncology. 2005, 27(3):823-830.

Li hua Qiu, Wen Di, Qin Jiang, Erica Schefeller, Steve Derby, Jian Yang, Nicola Kouttab, Harold Wanebo, Bingfang Yan, Yinsheng Wan. Targeted Inhibition of Transient Activation of the EGFR-mediated Cell Survival Pathway Enhances Paclitaxel-induced Ovarian Cell Death. International Journal of Oncology. 2005, 27(5):1441-1448.

季芳、张宁、狄文、廖秦平、王文、赵晓明、孙赟、刘朝晖.健康体检妇女阴道菌群状况及相关知识问卷调查分析.《中华妇产科杂志》.2009, 44(1):9-12.

戴岚、邱丽华、狄文、丁传伟.TWEAK对人卵巢癌细胞HO-8910PM侵袭转移的影响及其机制的研究.《现代妇产科进展》.2009, 18(1):35-38.

冯勤梅、吴霞、王颖、葛海良、狄文.紫杉醇联合顺铂诱导下的凋亡卵巢癌细胞对树突细胞提呈功能影响.《细胞与分子免疫学杂志》.2009, 25(1)：38-41.

冯勤梅、王颖、葛海良、吴霞、狄文. 紫杉醇联合顺铂诱导的凋亡卵巢癌细胞免疫原性.《中国肿瘤生物学治疗杂志》.2009, 16(2):130-135.

高华、施君、葛盛芳、狄文.RNA干扰技术抑制卵巢上皮性癌细胞IGF1R基因表达及增强顺铂敏感性的实验研究.《中华妇产科杂志》. 2008,43(1):45-49.

王文、狄文、廖秦平、刘朝晖、张宁、张惠英、张岱、耿力、樊尚荣、胡丽娜. 外阴阴道假丝酵母菌病患者阴道人类防御素分泌及发病相关因素的研究. 《中华妇产科杂志》. 2008, 43(7):486-489.